Folic Acid Supplementation and Riboflavin Status

Folic acid supplementation and cancer risk: point.

Folate, a water-soluble B vitamin that is present naturally in foods (e.g., green leafy vegetables, asparagus, broccoli, Brussels sprouts, citrus fruit, legumes, dry cereals, whole grain, yeast, lima beans, liver, and other organ meats), and folic acid, the synthetic form of this vitamin that is used commercially in supplements and in fortified foods, have been considered an ideal nutritional f...

Folic acid supplementation during methotrexate treatment: nonsense?

histological changes, and therefore this was not adequate to demonstrate response. Given her prolonged course and poor muscle mass at this stage, we expected subtle clinical changes with minimal initial improvement in muscle strength. Infusions (5mg/kg) were administered at weeks 0, 2, 6 and 14. She continued with prednisone and mycophenolate. A remarkable response was observed in muscle streng...

Spina Bifida Defying Folic Acid Supplementation

Pre-conceptional supplementation of folic acid is well known to reduce the incidence of spina bifida. But Athena is frequently perplexed to see this anomaly occurring despite folate supplementation. In a largest Canadian study, De Wal et al [1] screened 1.9 million live births to study the effect of mass fortification. On comparing pre and post fortification periods they noted only 46% reductio...

Preconceptional folic acid supplementation in Japan

Although a recommendation for preconceptional folate supplementation was issued by the Japanese Ministry of Health and Welfare in 2000, and promotional efforts were made by various related academic societies, including the Japan Society of Obstetrics and Gynecology (JSOG) and the Japan Association of Obstetricians and Gynecologists (JAOG), uptake of folate supplementation has been insufficient....

Folic Acid Supplementation: to Advise or not to Advise?